How did one of modern medicine’s most infamous treatments become accepted practice? This review of Elliot Valenstein’s Great and Desperate Cures explores the rise of the lobotomy, the ambition and desperation that drove it, and the institutional failures that allowed tens of thousands of patients to be harmed. It is a gripping history, and an unsettling warning about what can happen when urgent demand, weak safeguards, professional incentives, and uncritical enthusiasm collide.
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